SOC Drugs

# 1. Target: GSR

Drugs

Model Evidence

7 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


Drugs in GBM Trials

# 1. Target: RRM2

Drugs

Model Evidence

12 regulons containing the target(s), RRM2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


2. Target: TYMS

Drugs

Model Evidence

2 regulons containing the target(s), TYMS are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


3. Target: ALK

Drugs

Model Evidence

2 regulons containing the target(s), ALK are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


FDA Approved Drugs

# 1. Target: MAOB

Drugs

Model Evidence

3 regulons containing the target(s), MAOB are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


2. Target: TYMS

Drugs

Model Evidence

2 regulons containing the target(s), TYMS are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


3. Target: ALK

Drugs

Model Evidence

2 regulons containing the target(s), ALK are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


4. Target: SV2A

Drugs

Model Evidence

2 regulons containing the target(s), SV2A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


5. Target: KEAP1

Drugs

Model Evidence

4 regulons containing the target(s), KEAP1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


6. Target: VKORC1

Drugs

Model Evidence

2 regulons containing the target(s), VKORC1 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_UNFOLDED_PROTEIN_RESPONSE

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


7. Target: GSR

Drugs

Model Evidence

7 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


8. Target: ABL1

Drugs

Model Evidence

5 regulons containing the target(s), ABL1 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


9. Target: LOXL2

Drugs

Model Evidence

1 regulons containing the target(s), LOXL2 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_UNFOLDED_PROTEIN_RESPONSE

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


10. Target: BSG

Drugs

Model Evidence

2 regulons containing the target(s), BSG are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


11. Target: NDUFA13

Drugs

Model Evidence

5 regulons containing the target(s), NDUFA13 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


12. Target: TSG101

Drugs

Model Evidence

2 regulons containing the target(s), TSG101 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


13. Target: NOTCH1

Drugs

Model Evidence

4 regulons containing the target(s), NOTCH1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


14. Target: ABAT

Drugs

Model Evidence

17 regulons containing the target(s), ABAT are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


15. Target: CHKA

Drugs

Model Evidence

3 regulons containing the target(s), CHKA are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


16. Target: NQO1

Drugs

Model Evidence

2 regulons containing the target(s), NQO1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


17. Target: PLA2G2A

Drugs

Model Evidence

2 regulons containing the target(s), PLA2G2A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


18. Target: ELN

Drugs

Model Evidence

1 regulons containing the target(s), ELN are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


19. Target: TRPV4

Drugs

Model Evidence

1 regulons containing the target(s), TRPV4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


20. Target: RRM2

Drugs

Model Evidence

12 regulons containing the target(s), RRM2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


21. Target: EEF2

Drugs

Model Evidence

10 regulons containing the target(s), EEF2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


22. Target: MAPK1,MAPK3

Drugs

Model Evidence

18 regulons containing the target(s), MAPK1,MAPK3 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


23. Target: HSPA8

Drugs

Model Evidence

27 regulons containing the target(s), HSPA8 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


24. Target: ATP1A1

Drugs

Model Evidence

66 regulons containing the target(s), ATP1A1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


25. Target: PLA2G2A,PLA2G5

Drugs

Model Evidence

7 regulons containing the target(s), PLA2G2A,PLA2G5 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


26. Target: SLC6A9

Drugs

Model Evidence

13 regulons containing the target(s), SLC6A9 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


27. Target: APP

Drugs

Model Evidence

35 regulons containing the target(s), APP are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


28. Target: SOD1

Drugs

Model Evidence

5 regulons containing the target(s), SOD1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


29. Target: ACVR2B

Drugs

Model Evidence

5 regulons containing the target(s), ACVR2B are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


30. Target: OXTR

Drugs

Model Evidence

9 regulons containing the target(s), OXTR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots

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